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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RYR3
All Species:
3.03
Human Site:
S4121
Identified Species:
7.41
UniProt:
Q15413
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15413
NP_001027.3
4870
551932
S4121
E
E
E
D
E
D
S
S
Y
V
L
E
I
A
G
Chimpanzee
Pan troglodytes
XP_514296
5018
570278
E4271
G
R
S
A
N
K
E
E
S
E
K
E
R
P
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536330
4972
565017
E4225
E
R
S
V
S
K
E
E
S
E
K
E
K
P
E
Cat
Felis silvestris
Mouse
Mus musculus
NP_808320
4888
554548
S4139
E
E
E
E
D
E
D
S
A
Y
S
I
E
T
E
Rat
Rattus norvegicus
XP_001080527
4901
555534
D4152
E
E
E
E
E
D
E
D
S
Y
S
V
E
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518548
2719
302048
N2047
E
E
E
L
L
M
I
N
G
L
G
D
I
M
N
Chicken
Gallus gallus
NP_996757
4869
552752
C4122
L
R
K
I
E
E
P
C
Y
V
V
D
I
G
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922113
4863
550481
L4121
E
E
E
E
E
E
E
L
H
S
L
L
E
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24498
5127
580994
Y4400
R
D
T
A
Y
S
S
Y
M
S
E
E
E
E
E
Honey Bee
Apis mellifera
XP_392217
5083
576621
K4340
E
E
S
G
G
I
G
K
A
R
E
S
S
Y
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.6
N.A.
68
N.A.
95.6
94.4
N.A.
45.3
87.5
N.A.
77.4
N.A.
45
45.5
N.A.
N.A.
Protein Similarity:
100
80.9
N.A.
81.4
N.A.
97.5
96.7
N.A.
50.2
93.9
N.A.
87.9
N.A.
62.9
63.9
N.A.
N.A.
P-Site Identity:
100
6.6
N.A.
13.3
N.A.
26.6
33.3
N.A.
26.6
26.6
N.A.
33.3
N.A.
13.3
13.3
N.A.
N.A.
P-Site Similarity:
100
6.6
N.A.
13.3
N.A.
46.6
40
N.A.
46.6
53.3
N.A.
53.3
N.A.
20
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
20
0
0
0
0
20
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
10
20
10
10
0
0
0
20
0
0
10
% D
% Glu:
70
60
50
30
40
30
40
20
0
20
20
40
40
10
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
10
0
10
0
10
0
10
0
0
20
10
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
10
10
0
0
0
0
10
30
10
0
% I
% Lys:
0
0
10
0
0
20
0
10
0
0
20
0
10
0
0
% K
% Leu:
10
0
0
10
10
0
0
10
0
10
20
10
0
0
10
% L
% Met:
0
0
0
0
0
10
0
0
10
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
0
0
20
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
30
0
0
0
0
0
0
0
10
0
0
10
0
0
% R
% Ser:
0
0
30
0
10
10
20
20
30
20
20
10
10
0
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
10
% T
% Val:
0
0
0
10
0
0
0
0
0
20
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
10
20
20
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _